Priscilla Mantik
Sunesis (United States)(US)
Publications by Year
Research Areas
Cytokine Signaling Pathways and Interactions, NF-κB Signaling Pathways, Protein purification and stability, Crystallization and Solubility Studies, Protein Structure and Dynamics
Most-Cited Works
- → Lead identification of novel and selective TYK2 inhibitors(2013)122 cited
- → Lead Optimization of a 4-Aminopyridine Benzamide Scaffold To Identify Potent, Selective, and Orally Bioavailable TYK2 Inhibitors(2013)97 cited
- → Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model(2017)20 cited
- → Cyclodextrin Reduces Intravenous Toxicity of a Model Compound(2019)14 cited
- → Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling(2025)7 cited
- → Predicting Long-Term Stability of an Oral Delivered Antibody Drug Product with Accelerated Stability Assessment Program Modeling(2023)6 cited
- → Probing the Protein–Excipient Interaction in the Orally Delivered Protein by Solid-State Hydrogen–Deuterium Exchange Mass Spectrometry and Molecular Dynamics(2023)4 cited
- → Tyk2 (JH1) in complex with adenosine di-phosphate(2012)
- → In Vivo Tolerability of Supersaturation-Based Solubilization Strategies(2016)