Vı́ctor Segarra
Almirall (Spain)(ES)
Publications by Year
Research Areas
Phosphodiesterase function and regulation, Phenothiazines and Benzothiazines Synthesis and Activities, Synthesis and Biological Evaluation, Computational Drug Discovery Methods, Synthesis and biological activity
Most-Cited Works
- → Setup and validation of shake-flask procedures for the determination of partition coefficients (logD) from low drug amounts(2015)213 cited
- → Synthesis and Biological Evaluation of 3,4-Diaryloxazolones: A New Class of Orally Active Cyclooxygenase-2 Inhibitors(1999)98 cited
- → Novel Heterocyclic-Fused Pyridazinones as Potent and Selective Phosphodiesterase IV Inhibitors(1997)72 cited
- → Discovery of Novel Quaternary Ammonium Derivatives of (3R)-Quinuclidinol Esters as Potent and Long-Acting Muscarinic Antagonists with Potential for Minimal Systemic Exposure after Inhaled Administration: Identification of (3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane Bromide (Aclidinium Bromide)(2009)70 cited
- → Benzyl Derivatives of 2,1,3-Benzo- and Benzothieno[3,2-a]thiadiazine 2,2-Dioxides: First Phosphodiesterase 7 Inhibitors(2000)70 cited
- → Phosphodiesterase inhibitory properties of losartan. design and synthesis of new lead compounds(1998)59 cited
- → Combined anti CXC receptors 1 and 2 therapy is a promising anti-inflammatory treatment for respiratory diseases by reducing neutrophil migration and activation(2015)45 cited
- → Design, Synthesis, and Biological Activities of New Thieno[3,2-d]pyrimidines as Selective Type 4 Phosphodiesterase Inhibitors(1998)44 cited
- → Design, Synthesis, and Structure−Activity Relationships of 1-,3-,8-, and 9-Substituted-9-deazaxanthines at the Human A2BAdenosine Receptor(2005)38 cited
- → Synthesis and evaluation of quinazoline derivatives as phosphodiesterase 7 inhibitors(2013)36 cited