Humberto Arzeno
Roche (United States)(US)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Melanoma and MAPK Pathways, Chemical Synthesis and Reactions, Computational Drug Discovery Methods, Synthesis and biological activity
Most-Cited Works
- → Design and Synthesis of 4-Azaindoles as Inhibitors of p38 MAP Kinase(2003)95 cited
- → Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase(2011)74 cited
- → 3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: Design and development to a highly selective lead(2011)27 cited
- → Development of amino-pyrimidine inhibitors of c-Jun N-terminal kinase (JNK): Kinase profiling guided optimization of a 1,2,3-benzotriazole lead(2012)27 cited
- → Design and synthesis of orally active inhibitors of TNF synthesis as anti-rheumatoid arthritis drugs(2003)19 cited
- → Dearomatisation of 2-naphthol by oxidative nucleophilic substitution and oxidative electrophilic substitution(1984)15 cited
- → Mild Reductive Cleavage of the 9-Anthracenesulfonamido Function. The 9-Anthracenesulfonyl (Ans) Group: A New Approach to the Protection of the Guanidino Function of Arginine Residues in Peptide Synthesis(1988)13 cited
- → Temporary serine protection in solid phase synthesis of LH‐RH analogs(1993)11 cited
- → A Simple, Efficient Synthesis of N6-[bis(ethylamino) methylene]-N2-[(1,1-dimethylethoxy)carbonyl]-lysine (Boc-diethylhomoarginine)(1990)7 cited
- → ChemInform Abstract: SYNTHESIS OF 10(S)‐METHYLCODEINE AND 10(S)‐METHYLMORPHINE(1980)