Shaun Fillery
AstraZeneca (United Kingdom)(GB)AstraZeneca (Singapore)(SG)AstraZeneca (Switzerland)(CH)
Publications by Year
Research Areas
Synthesis and Catalytic Reactions, Catalytic C–H Functionalization Methods, Protein Degradation and Inhibitors, Synthesis and Biological Evaluation, Protein Kinase Regulation and GTPase Signaling
Most-Cited Works
- → Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): A Potent and Selective Inhibitor of ATR Protein Kinase with Monotherapy in Vivo Antitumor Activity(2013)214 cited
- → Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6(2018)136 cited
- → Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival(2016)135 cited
- → Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C(2020)83 cited
- → Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors(2017)78 cited
- → Amination of ethers using chloramine-T hydrate and a copper(i) catalyst(2004)76 cited