Lance Ostrom
Publications by Year
Research Areas
Cancer Mechanisms and Therapy, Microtubule and mitosis dynamics, Hedgehog Signaling Pathway Studies, Cancer Cells and Metastasis, Wnt/β-catenin signaling in development and cancer
Most-Cited Works
- → Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma(2010)553 cited
- → Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene(2001)295 cited
- → Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies(2010)153 cited
- → Reduced Pax2 Gene Dosage Increases Apoptosis and Slows the Progression of Renal Cystic Disease(2000)111 cited
- → Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction(2014)104 cited
- → Discovery and Optimization of HKT288, a Cadherin-6–Targeting ADC for the Treatment of Ovarian and Renal Cancers(2017)52 cited
- → Abstract 4290: The smoothened antagonist NVP-LDE225 targets stroma and cancer stem cells in primary human pancreatic tumor xenografts(2010)4 cited
- → Abstract 2974: Targeting cadherin-6 (CDH6) with an antibody-drug conjugate for the treatment of ovarian and renal cancer(2016)1 cited
- → Gene expression analysis in human hair bulbs as a potential pharmacodynamic readout in the LDE225 clinical program.(2010)1 cited
- → Abstract A41: The preanalytic impact of simulated ischemia on PI3K biomarkers(2009)1 cited