Edward W. Petrillo
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Protein Hydrolysis and Bioactive Peptides, Renin-Angiotensin System Studies, Enzyme function and inhibition, Pharmacogenetics and Drug Metabolism
Most-Cited Works
- → Angiotensin‐converting enzyme inhibitors: Medicinal chemistry and biological actions(1982)194 cited
- → .alpha.-Hydroxy Phosphinyl-Based Inhibitors of Human Renin(1995)190 cited
- → (Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline, a novel orally active inhibitor of ACE(1988)106 cited
- → Activated ketone based inhibitors of human renin(1993)65 cited
- → Angiotensin-converting enzyme inhibitors: importance of the amide carbonyl of mercaptoacyl amino acids for hydrogen bonding to the enzyme(1982)51 cited
- → Orally Active Squalene Synthase Inhibitors: Bis((acyloxy)alkyl) Prodrugs of the α-Phosphonosulfonic Acid Moiety(1996)48 cited
- → Rational Design and Biochemical Utility of Specific Inhibitors of Angiotensin-Converting Enzyme(1987)47 cited
- Positron-labeled angiotensin-converting enzyme (ACE) inhibitor: fluorine-18-fluorocaptopril. Probing the ACE activity in vivo by positron emission tomography.(1991)
- → Fosinopril, a Phosphinic Acid Inhibitor of Angiotensin I Converting Enzyme: In Vitro and Preclinical In Vivo Pharmacology(1989)46 cited
- → Synthesis of 2-phosphonopyrrolidine and its substitution for proline in an inhibitor of angiotensin-converting enzyme(1979)44 cited