Alex B. Burgin
Broad Institute(US)Broad Institute(US)Centers for Disease Control and Prevention(US)Georgia Institute of Technology(US)National Center for Emerging and Zoonotic Infectious Diseases(US)
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, RNA and protein synthesis mechanisms, Bacteriophages and microbial interactions, DNA and Nucleic Acid Chemistry, Bioactive Compounds and Antitumor Agents
Most-Cited Works
- → Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases(2012)1,323 cited
- → The mechanism of topoisomerase I poisoning by a camptothecin analog(2002)799 cited
- → Structures of Three Classes of Anticancer Agents Bound to the Human Topoisomerase I−DNA Covalent Complex(2005)531 cited
- → A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases.(1996)403 cited
- → Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety(2009)392 cited
- → Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets(2012)250 cited