Gabriel Martínez-Botella
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Synthesis and biological activity, PI3K/AKT/mTOR signaling in cancer, Colorectal Cancer Treatments and Studies, Cytokine Signaling Pathways and Interactions
Most-Cited Works
- → Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib)(2017)227 cited
- → Structure-Guided Design of Potent and Selective Pyrimidylpyrrole Inhibitors of Extracellular Signal-Regulated Kinase (ERK) Using Conformational Control(2009)145 cited
- → Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors(2007)119 cited
- → Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases(2015)87 cited
- → Antibacterial Inhibitors of Gram-Positive Thymidylate Kinase: Structure–Activity Relationships and Chiral Preference of a New Hydrophobic Binding Region(2014)61 cited
- → Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK)(2012)54 cited
- → Structural Basis for Isoform Selectivity in a Class of Benzothiazole Inhibitors of Phosphoinositide 3-Kinase γ(2014)51 cited
- → Discovery of the First Orally Available, Selective KNa1.1 Inhibitor: In Vitro and In Vivo Activity of an Oxadiazole Series(2021)49 cited
- → In Vivo Validation of Thymidylate Kinase (TMK) with a Rationally Designed, Selective Antibacterial Compound(2012)44 cited
- → Sulfonylpiperidines as novel, antibacterial inhibitors of Gram-positive thymidylate kinase (TMK)(2012)32 cited