Patrick A. Holt
University of Louisville(US)James Graham Brown Foundation(US)
Publications by Year
Research Areas
DNA and Nucleic Acid Chemistry, Advanced biosensing and bioanalysis techniques, RNA Interference and Gene Delivery, Cancer therapeutics and mechanisms, RNA and protein synthesis mechanisms
Most-Cited Works
- → Molecular Docking of Intercalators and Groove-Binders to Nucleic Acids Using Autodock and Surflex(2008)221 cited
- → Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4(2012)64 cited
- → Structure-based drug design: From nucleic acid to membrane protein targets(2009)57 cited
- → Discovery of novel triple helical DNA intercalators by an integrated virtual and actual screening platform(2009)40 cited
- → Polymorphism and resolution of oncogene promoter quadruplex-forming sequences(2011)38 cited
- → A discovery funnel for nucleic acid binding drug candidates(2010)25 cited
- → Prediction of noncovalent Drug/DNA interaction using computational docking models: Studies with over 1350 launched drugs(2013)24 cited
- → Mammary carcinogen-protein binding potentials: novel and biologically relevant structure–activity relationship model descriptors(2010)3 cited
- → Evidence for the contribution of non-covalent steroid interactions between DNA and topoisomerase in the genotoxicity of steroids(2014)2 cited
- → ChemInform Abstract: Molecular Docking of Intercalators and Groove‐Binders to Nucleic Acids Using Autodock and Surflex.(2008)