Taylor L. Mighell
Centre for Genomic Regulation(ES)CRG Services (United States)(US)
Publications by Year
Research Areas
CRISPR and Genetic Engineering, Chromosomal and Genetic Variations, PI3K/AKT/mTOR signaling in cancer, Receptor Mechanisms and Signaling, Advanced biosensing and bioanalysis techniques
Most-Cited Works
- → A Saturation Mutagenesis Approach to Understanding PTEN Lipid Phosphatase Activity and Genotype-Phenotype Relationships(2018)229 cited
- → AAV-Mediated CRISPR/Cas9 Gene Editing in Murine Phenylketonuria(2019)92 cited
- → An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships(2020)58 cited
- → A Sort-Seq Approach to the Development of Single Fluorescent Protein Biosensors(2021)18 cited
- → SUNi mutagenesis: Scalable and uniform nicking for efficient generation of variant libraries(2023)15 cited
- → A pharmacological chaperone stabilizer rescues the expression of the vast majority of pathogenic variants in a G protein-coupled receptor(2024)6 cited
- → A saturation mutagenesis approach to understanding PTEN lipid phosphatase activity and genotype-phenotypes relationships(2018)3 cited
- → A small molecule stabilizer rescues the surface expression of nearly all missense variants in a GPCR(2025)2 cited
- → GPCR-MAPS: high-resolution functional and allosteric mapping of G protein-coupled receptor activation and bias(2025)2 cited