Grace Yan
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Cholesterol and Lipid Metabolism, Pharmacogenetics and Drug Metabolism, Sphingolipid Metabolism and Signaling, Drug-Induced Hepatotoxicity and Protection
Most-Cited Works
- → Discovery of XL335 (WAY-362450), a Highly Potent, Selective, and Orally Active Agonist of the Farnesoid X Receptor (FXR)(2009)161 cited
- → Liver X Receptor (LXR) partial agonists: Biaryl pyrazoles and imidazoles displaying a preference for LXRβ(2014)42 cited
- → Determination of Intracellular Unbound Concentrations and Subcellular Localization of Drugs in Rat Sandwich-Cultured Hepatocytes Compared with Liver Tissue(2013)34 cited
- → Discovery of Highly Potent Liver X Receptor β Agonists(2016)33 cited
- → Use of in vitro data in developing a physiologically based pharmacokinetic model: Carbaryl as a case study(2014)32 cited
- → Oligomerization is required for the activity of recombinant soluble LOX‐1(2009)28 cited
- → Mechanisms Underlying Differences in Systemic Exposure of Structurally Similar Active Metabolites: Comparison of Two Preclinical Hepatic Models(2011)23 cited
- → A Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite Pair(2011)22 cited
- → Choices in hemodialysis therapies: variants, personalized therapy and application of evidence-based medicine(2021)22 cited
- → Mice treated with a myostatin/GDF-8 decoy receptor, ActRIIB-Fc, exhibit a tremendous increase in bone mass(2008)16 cited