Sandra Handschuh
Boehringer Ingelheim (Germany)(DE)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Chemical Synthesis and Analysis, Protein Structure and Dynamics, Organometallic Complex Synthesis and Catalysis, Synthesis and characterization of novel inorganic/organometallic compounds
Most-Cited Works
- → Design, Synthesis, and Evaluation of Indolinones as Triple Angiokinase Inhibitors and the Discovery of a Highly Specific 6-Methoxycarbonyl-Substituted Indolinone (BIBF 1120)(2009)230 cited
- → Superposition of Three-Dimensional Chemical Structures Allowing for Conformational Flexibility by a Hybrid Method(1998)89 cited
- → Heterocyclic thrombin inhibitors. Part 2: quinoxalinone derivatives as novel, potent antithrombotic agents(2003)78 cited
- → Stabilizing of a Globular Protein by a Highly Complex Water Network: A Molecular Dynamics Simulation Study on Factor Xa(2010)70 cited
- → Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo(2017)43 cited
- → Theoretical Prediction of Hydrogen Bond Strength for Use in Molecular Modeling(2009)39 cited
- → The Search for the Spatial and Electronic Requirements of a Drug(2000)24 cited
- → A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state(2020)19 cited
- → The Presence and Absence of Agostic Electrostatic Si−H···M Interactions in [M{Me2Si(H)N-t-Bu}] (M = Li, Mg1/2) Species(1997)16 cited
- → New chelating silylamido ligands: syntheses and X-ray crystal structures of lithium and magnesium derivatives of [t-Bu–HN–SiMe2–o-C6H4–X] (X=OMe, NMe2, CH2NMe2, CF3)(1998)14 cited