Gordon W. Rewcastle
Cancer Society of New Zealand(NZ)
Publications by Year
Research Areas
Synthesis and biological activity, PI3K/AKT/mTOR signaling in cancer, Cancer therapeutics and mechanisms, Bioactive Compounds and Antitumor Agents, Synthesis and Characterization of Heterocyclic Compounds
Most-Cited Works
- → Tyrosine Kinase Inhibitors. 8. An Unusually Steep Structure−Activity Relationship for Analogues of 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a Potent Inhibitor of the Epidermal Growth Factor Receptor(1996)321 cited
- → Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of minimal DNA-intercalating agents which may not act via topoisomerase II(1990)309 cited
- → Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor: 4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions(2000)263 cited
- → Tyrosine kinase inhibitors. 5. Synthesis and structure-activity relationships for 4-[(phenylmethyl)amino]- and 4-(phenylamino)quinazolines as potent adenosine 5'-triphosphate binding site inhibitors of the tyrosine kinase domain of the epidermal growth factor receptor.(1995)260 cited
- → Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling(2007)226 cited