Tarra Fuchs
Sunesis (United States)(US)
Publications by Year
Research Areas
Synthesis and Biological Evaluation, Phenothiazines and Benzothiazines Synthesis and Activities, Antibiotics Pharmacokinetics and Efficacy, Antibiotic Resistance in Bacteria, Computational Drug Discovery Methods
Most-Cited Works
- → 3-Amino-1,2,4-benzotriazine 4-Oxide: Characterization of a New Metabolite Arising from Bioreductive Processing of the Antitumor Agent 3-Amino-1,2,4-benzotriazine 1,4-Dioxide (Tirapazamine)(2000)67 cited
- → Reaction of the Hypoxia-Selective Antitumor Agent Tirapazamine with a C1‘-Radical in Single-Stranded and Double-Stranded DNA: The Drug and Its Metabolites Can Serve as Surrogates for Molecular Oxygen in Radical-Mediated DNA Damage Reactions(1999)62 cited
- → A mass spectrometry study of tirapazamine and its metabolites: Insights into the mechanism of metabolic transformations and the characterization of reaction intermediates(2003)38 cited
- → Effects of Amino Acid Chirality and the Chemical Linker on the Cell Permeation Characteristics of Cyclic Prodrugs of Opioid Peptides(2006)18 cited
- → Crystal structure of 3-amino-5-methyl-1,2,4-benzotriazine 1-oxide: Evidence for formation of a covalent attachment between a carbon-centered radical and the antitumor agent tirapazamine(2001)5 cited
- → Case Study: Cefuroxime Axetil: An Oral Prodrug of Cefuroxime(2008)5 cited
- → Case Study: Cefditoren Pivoxil: An Oral Prodrug of Cefditoren(2008)4 cited