Xavier Billot
Publications by Year
Research Areas
Inflammatory mediators and NSAID effects, Chemical Synthesis and Analysis, Marine Sponges and Natural Products, Cell death mechanisms and regulation, Estrogen and related hormone effects
Most-Cited Works
- → Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis(2007)652 cited
- → The Small Molecule GMX1778 Is a Potent Inhibitor of NAD + Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors(2009)219 cited
- → Selective Entry to the Dimeric or Oligomeric Pyridinium Sponge Macrocycles via Aminopentadienal Derivatives. Possible Biogenetic Relevance with Manzamine Alkaloids(1998)89 cited
- → Discovery of a potent and selective agonist of the prostaglandin EP4 receptor(2003)83 cited
- → Discovery and Synthesis of a Potent, Selective and Orally Bioavailable EP4 Receptor Agonist(2004)53 cited
- → A Scalable Process for the Synthesis of the Bcl Inhibitor Obatoclax(2007)30 cited
- → Discovery of nanomolar ligands with novel scaffolds for the histamine H4 receptor by virtual screening(2016)11 cited
- → Bariatric Surgery Improves the Atherogenic Profile of Circulating Methylarginines in Obese Patients: Results from a Pilot Study(2021)10 cited
- → Synthesis and evaluation of a 2-benzothiazolylphenylmethyl ether class of histamine H4 receptor antagonists(2016)8 cited
- → Obatoclax (GX15-070) Is a Potent Antagonist of Constitutive Mcl-1/Bak Interactions in Intact Mitochondrial Membrane and Synergizes with Bortezomib in Mantle Cell Lymphoma.(2006)5 cited