George R. Pettit
Arizona State University(US)
Publications by Year
Research Areas
Marine Sponges and Natural Products, Microbial Natural Products and Biosynthesis, Steroid Chemistry and Biochemistry, Synthetic Organic Chemistry Methods, Chemical Synthesis and Analysis
Most-Cited Works
- → Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4(1989)785 cited
- → Isolation and structure of bryostatin 1(1982)654 cited
- Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature.(1997)
- → The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10(1987)573 cited
- → Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin(1989)414 cited
- → Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data(1991)376 cited