Elizabeth Mahan

Publications by Year

Research Areas

Microtubule and mitosis dynamics, Protein Structure and Dynamics, Enzyme Structure and Function, Advanced biosensing and bioanalysis techniques, Photosynthetic Processes and Mechanisms

Most-Cited Works

• → Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (2S)-4-(2,5-Difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the Treatment of Taxane-Refractory Cancer(2008)156 cited
• → Quantitation of small molecules using high‐resolution accurate mass spectrometers – a different approach for analysis of biological samples(2009)130 cited
• → Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP(2006)62 cited
• → Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP(2007)40 cited
• → Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors(2006)37 cited
• → Quantitation of Physiological and Biochemical Barriers to siRNA Liver Delivery via Lipid Nanoparticle Platform(2014)35 cited
• → Kinesin spindle protein (KSP) inhibitors. Part 6: Design and synthesis of 3,5-diaryl-4,5-dihydropyrazole amides as potent inhibitors of the mitotic kinesin KSP(2007)25 cited
• → Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP(2007)18 cited
• Utilization of Mouse Automated Blood Sampling (ABS) for Serial Plasma Pharmacokinetic (PK) Studies(2015)