Blake E. Smith
Harvard University(US)Center for Cancer Research(US)
Publications by Year
Research Areas
CAR-T cell therapy research, Virus-based gene therapy research, Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, T-cell and B-cell Immunology
Most-Cited Works
- → Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead(2017)876 cited
- → The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study(2017)650 cited
- → Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase(2019)507 cited
- → Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth(2017)197 cited
- → Antigen identification and high-throughput interaction mapping by reprogramming viral entry(2022)107 cited
- → A biomaterial platform for T cell-specific gene delivery(2024)4 cited
- → Scalable TCR synthesis and screening enables antigen reactivity mapping in vitiligo(2025)3 cited
- → Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells(2024)3 cited
- → Library-based single-cell analysis of CAR signaling reveals drivers of in vivo persistence(2025)2 cited