Graciela B. Arhancet

Publications by Year

Research Areas

Estrogen and related hormone effects, Hormonal Regulation and Hypertension, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Surfactants and Colloidal Systems

Most-Cited Works

• → Discovery of (3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy(2010)91 cited
• → Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation(2012)48 cited
• → Discovery of Novel Cyanodihydropyridines as Potent Mineralocorticoid Receptor Antagonists(2010)46 cited
• → Stereochemical Requirements for the Mineralocorticoid Receptor Antagonist Activity of Dihydropyridines(2010)38 cited
• Insulin sensitizing pharmacology of thiazolidinediones correlates with mitochondrial gene expression rather than activation of PPAR gamma.(2007)
• → Identification of (R)-6-(1-(4-Cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl)-2-methoxynicotinic Acid, a Highly Potent and Selective Nonsteroidal Mineralocorticoid Receptor Antagonist(2014)27 cited
• → Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design(2012)27 cited
• → Thermolysis of a Tertiary Alkoxyamine. Recombination and Disproportionation of α-Phenethyl/Diethyl Nitroxyl Radical Pairs(1997)19 cited
• → Thiazolidinediones inhibit the progression of established hypertension in the Dahl salt-sensitive rat(2007)13 cited
• → Insulin Sensitizing Pharmacology of Thiazolidinediones Correlates with Mitochondrial Gene Expression rather than Activation of PPARγ(2007)13 cited