Hugues Dolgos
Servier (France)(FR)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Computational Drug Discovery Methods, Drug Transport and Resistance Mechanisms, Drug-Induced Hepatotoxicity and Protection, Statistical Methods in Clinical Trials
Most-Cited Works
- → In Vitro Approach to Assess the Potential for Risk of Idiosyncratic Adverse Reactions Caused by Candidate Drugs(2012)212 cited
- → Early integration of pharmacokinetic and dynamic reasoning is essential for optimal development of lead compounds: strategic considerations(2009)102 cited
- → Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development(2010)102 cited
- → Evaluating the Role of Solubility in Oral Absorption of Poorly Water‐Soluble Drugs Using Physiologically‐Based Pharmacokinetic Modeling(2019)93 cited
- → Requirements to Establishing Confidence in Physiologically Based Pharmacokinetic (PBPK) Models and Overcoming Some of the Challenges to Meeting Them(2019)74 cited
- → The right compound in the right assay at the right time: an integrated discovery DMPK strategy(2012)60 cited
- → Translational Medicine Guide transforms drug development processes: the recent Merck experience(2016)57 cited
- → Utility of In Vitro Systems and Preclinical Data for the Prediction of Human Intestinal First-Pass Metabolism during Drug Discovery and Preclinical Development(2013)45 cited
- → Evaluation of the Use of Static and Dynamic Models to Predict Drug-Drug Interaction and Its Associated Variability: Impact on Drug Discovery and Early Development(2012)45 cited
- → A comparative evaluation of models to predict human intestinal metabolism from nonclinical data(2017)38 cited