Giulia Bortolussi
International Centre for Genetic Engineering and Biotechnology(IT)
Publications by Year
Research Areas
Neonatal Health and Biochemistry, Heme Oxygenase-1 and Carbon Monoxide, Pancreatic function and diabetes, Virus-based gene therapy research, CRISPR and Genetic Engineering
Most-Cited Works
- → Life-Long Correction of Hyperbilirubinemia with a Neonatal Liver-Specific AAV-Mediated Gene Transfer in a Lethal Mouse Model of Crigler–Najjar Syndrome(2014)81 cited
- → Rescue of bilirubin‐induced neonatal lethality in a mouse model of Crigler‐Najjar syndrome type I by AAV9‐mediated gene transfer(2011)75 cited
- → Gene Therapy in Patients with the Crigler–Najjar Syndrome(2023)64 cited
- → Promoterless gene targeting without nucleases rescues lethality of a Crigler‐Najjar syndrome mouse model(2017)61 cited
- → Bilirubin‐Induced Oxidative Stress Leads to DNA Damage in the Cerebellum of Hyperbilirubinemic Neonatal Mice and Activates DNA Double‐Strand Break Repair Pathways in Human Cells(2018)61 cited
- → A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome(2016)60 cited
- → Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome(2018)59 cited
- → Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases(2019)59 cited
- → Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model(2017)50 cited
- → Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia(2018)49 cited