John Breen
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, Antibiotic Resistance in Bacteria, Antibiotics Pharmacokinetics and Efficacy, Biochemical and Molecular Research, Tuberculosis Research and Epidemiology
Most-Cited Works
- → Characterization of seed‐specific benzoyloxyglucosinolate mutations in Arabidopsis thaliana(2007)101 cited
- → Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity(2011)101 cited
- → Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pKa: Antibacterial Agents with an Improved Safety Profile(2012)89 cited
- → Antibacterial Inhibitors of Gram-Positive Thymidylate Kinase: Structure–Activity Relationships and Chiral Preference of a New Hydrophobic Binding Region(2014)61 cited
- → Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors(2016)60 cited
- → Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK)(2012)54 cited
- → In Vivo Validation of Thymidylate Kinase (TMK) with a Rationally Designed, Selective Antibacterial Compound(2012)44 cited
- → 4,5-Disubstituted 6-Aryloxy-1,3-dihydrobenzo[c][1,2]oxaboroles Are Broad-Spectrum Serine β-Lactamase Inhibitors(2015)36 cited
- → Optimization of physicochemical properties and safety profile of novel bacterial topoisomerase type II inhibitors (NBTIs) with activity against Pseudomonas aeruginosa(2014)24 cited
- → Cefepime versus Ceftazidime as Empiric Therapy of Febrile Episodes in Neutropenic Patients(1997)11 cited