Dorothy Levorse
Merck & Co., Inc., Rahway, NJ, USA (United States)(US)
Publications by Year
Research Areas
Analytical Chemistry and Chromatography, Receptor Mechanisms and Signaling, Computational Drug Discovery Methods, Chemical Synthesis and Analysis, Crystallization and Solubility Studies
Most-Cited Works
- → (2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]- pyridin-6-ylphenyl)butanamide: A Selective α-Amino Amide Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes(2006)121 cited
- → Difluoroethylamines as an amide isostere in inhibitors of cathepsin K(2010)111 cited
- → Discovery of Vibegron: A Potent and Selective β3Adrenergic Receptor Agonist for the Treatment of Overactive Bladder(2015)101 cited
- → Ionization Behavior of Amino Lipids for siRNA Delivery: Determination of Ionization Constants, SAR, and the Impact of Lipid pKa on Cationic Lipid−Biomembrane Interactions(2011)86 cited
- → Inhibition of Stromelysin-1 (MMP-3) by P1‘-Biphenylylethyl Carboxyalkyl Dipeptides(1997)66 cited
- → Discovery and X-ray Crystallographic Analysis of a Spiropiperidine Iminohydantoin Inhibitor of β-Secretase(2008)59 cited
- → The discovery of sulfonylated dipeptides as Potent VLA-4 antagonists(2001)59 cited
- → A Spectroscopic Investigation of Losartan Polymorphs(1993)57 cited
- → pKa measurements for the SAMPL6 prediction challenge for a set of kinase inhibitor-like fragments(2018)54 cited
- → Octanol–water partition coefficient measurements for the SAMPL6 blind prediction challenge(2019)52 cited