Tarra Fuchs-Knotts
Sunesis (United States)(US)
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Chronic Lymphocytic Leukemia Research, Lymphoma Diagnosis and Treatment, Pharmacogenetics and Drug Metabolism, Angiogenesis and VEGF in Cancer
Most-Cited Works
- → DNA Strand Cleavage by the Phenazine Di-N-oxide Natural Product Myxin under Both Aerobic and Anaerobic Conditions(2011)58 cited
- → Water-soluble prodrugs of an Aurora kinase inhibitor(2009)21 cited
- → Isotopic Labeling Experiments That Elucidate the Mechanism of DNA Strand Cleavage by the Hypoxia-Selective Antitumor Agent 1,2,4-Benzotriazine 1,4-Di-N-oxide(2013)16 cited
- → Exploiting the Inherent Photophysical Properties of the Major Tirapazamine Metabolite in the Development of Profluorescent Substrates for Enzymes That Catalyze the Bioreductive Activation of Hypoxia-Selective Anticancer Prodrugs(2018)15 cited
- → Optimization of novel reversible Bruton’s tyrosine kinase inhibitors identified using Tethering-fragment-based screens(2019)15 cited
- → Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton’s tyrosine kinase inhibitors(2021)11 cited
- → Factors that Restrict the Cell Permeation of Cyclic Prodrugs of an Opioid Peptide, Part 3: Synthesis of Analogs Designed to have Improved Stability to Oxidative Metabolism(2012)8 cited
- → 378 POSTER Non-clinical pharmacokinetics, distribution and excretion of SNS-314, a novel, selective aurora kinase inhibitor(2007)