Atsuko Higashida
Chugai Pharma (United States)(US)
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Melanoma and MAPK Pathways, Monoclonal and Polyclonal Antibodies Research, Pharmacological Effects of Natural Compounds, Cancer Mechanisms and Therapy
Most-Cited Works
- → Oral Absorption of Poorly Water-Soluble Drugs: Computer Simulation of Fraction Absorbed in Humans from a Miniscale Dissolution Test(2006)273 cited
- → Hepatocellular carcinoma in a mouse model fed a choline‐deficient, L‐amino acid‐defined, high‐fat diet(2017)93 cited
- → Antiatherogenic effects of the antioxidant BO-653 in three different animal models(1998)89 cited
- → Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets(2023)89 cited
- → Correction of Permeability with Pore Radius of Tight Junctions in Caco-2 Monolayers Improves the Prediction of the Dose Fraction of Hydrophilic Drugs Absorbed by Humans(2004)83 cited
- → Prediction of oral drug absorption in humans by theoretical passive absorption model(2005)57 cited
- → Prediction of Drug-Drug Interactions based on Time-Dependent Inhibition from High Throughput Screening of Cytochrome P450 3A4 Inhibition(2009)42 cited
- → Selective TRK Inhibitor CH7057288 against TRK Fusion-Driven Cancer(2018)20 cited
- → Processing of Biopharmaceutical Profiling Data in Drug Discovery(2007)15 cited
- → In vivoapproach for the evaluation of mechanism-based inhibition of cytochrome P450 3A in rats(2008)11 cited