Wen-I Chang
Brown University(US)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Neuroblastoma Research and Treatments, Sarcoma Diagnosis and Treatment, Histone Deacetylase Inhibitors Research, Acute Myeloid Leukemia Research
Most-Cited Works
- → Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands(2017)913 cited
- → ONC201 and imipridones: Anti-cancer compounds with clinical efficacy(2020)163 cited
- → Early neutrophilic expression of vascular endothelial growth factor after traumatic brain injury(2003)88 cited
- → High risk of relapsed disease in patients with NK/T-cell chronic active Epstein-Barr virus disease outside of Asia(2021)27 cited
- Potent preclinical sensitivity to imipridone-based combination therapies in oncohistone H3K27M-mutant diffuse intrinsic pontine glioma is associated with induction of the integrated stress response, TRAIL death receptor DR5, reduced ClpX and apoptosis.(2021)
- → Molecular Targets for Novel Therapeutics in Pediatric Fusion-Positive Non-CNS Solid Tumors(2022)17 cited
- → Human IgA Monoclonal Antibodies Specific for a Major Ragweed Pollen Antigen(1995)10 cited
- → Anti-Leukemic Activity of STRO-002 a Novel Folate Receptor-α (FR-α)-Targeting ADC in Relapsed/Refractory CBF2AT3-GLIS2 AML(2022)7 cited
- Novel combination of imipridones and histone deacetylase inhibitors demonstrate cytotoxic effect through integrated stress response in pediatric solid tumors.(2023)
- → Abstract 3902: Novel therapeutic targeting of epigenetic aberrations in pediatric sarcomas through combination of ONC201 and HDAC inhibitors(2020)2 cited