Akifumi Kogame
Takeda (Japan)(JP)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Helicobacter pylori-related gastroenterology studies, Diabetes Treatment and Management, Gastroesophageal reflux and treatments, Inflammatory mediators and NSAID effects
Most-Cited Works
- → Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist(2010)247 cited
- → Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor(2019)67 cited
- → In patients with ulcerative colitis, adsorptive depletion of granulocytes and monocytes impacts mucosal level of neutrophils and clinically is most effective in steroid naïve patients(2008)62 cited
- → A CDC7 inhibitor sensitizes DNA-damaging chemotherapies by suppressing homologous recombination repair to delay DNA damage recovery(2021)25 cited
- → Radiographic Localization Study of a Novel Potassium-Competitive Acid Blocker, Vonoprazan, in the Rat Gastric Mucosa(2016)20 cited
- → Pharmacokinetic and Pharmacodynamic Modeling of Hedgehog Inhibitor TAK-441 for the Inhibition of Gli1 messenger RNA Expression and Antitumor Efficacy in Xenografted Tumor Model Mice(2013)19 cited
- → Disposition and metabolism of TAK-438 (vonoprazan fumarate), a novel potassium-competitive acid blocker, in rats and dogs(2016)18 cited
- → Time Course Study for Airway Inflammation and Responsiveness by Repeated Provocation of Aeroantigen in Guinea Pigs(1997)17 cited
- → Disposition and metabolism of the G protein-coupled receptor 40 agonist TAK-875 (fasiglifam) in rats, dogs, and humans(2018)16 cited
- → Development, validation and application of the liquid chromatography tandem mass spectrometry method for simultaneous quantification of azilsartan medoxomil (TAK-491), azilsartan (TAK-536), and its 2 metabolites in human plasma(2015)10 cited