Laurie P. Volak
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, Biochemical and Molecular Research, PI3K/AKT/mTOR signaling in cancer
Most-Cited Works
- → The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity(2019)2,188 cited
- → Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors(2019)691 cited
- → Curcuminoids Inhibit Multiple Human Cytochromes P450, UDP-Glucuronosyltransferase, and Sulfotransferase Enzymes, whereas Piperine Is a Relatively Selective CYP3A4 Inhibitor(2008)196 cited
- → Systematic Study of the Glutathione (GSH) Reactivity ofN-Arylacrylamides: 1. Effects of Aryl Substitution(2015)152 cited
- → Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C(2019)103 cited
- → Discovery and Optimization of a Series of 3-(3-Phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amines: Orally Bioavailable, Selective, and Potent ATP-Independent Akt Inhibitors(2012)99 cited
- → Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers(2012)90 cited
- → Systematic Study of the Glutathione Reactivity of N -Phenylacrylamides: 2. Effects of Acrylamide Substitution(2020)64 cited
- → Zinc Status Influences Zinc Transport by Porcine Brain Capillary Endothelial Cells(2002)29 cited
- → Role for protein kinase C delta in the functional activity of human UGT1A6: implications for drug–drug interactions between PKC inhibitors and UGT1A6(2010)23 cited