M.C. Van Zandt
Medical Discovery Partners (United States)(US)
Publications by Year
Research Areas
Carbohydrate Chemistry and Synthesis, Aldose Reductase and Taurine, Parasites and Host Interactions, Amino Acid Enzymes and Metabolism, Enzyme Catalysis and Immobilization
Most-Cited Works
- → Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-N-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications(2005)224 cited
- → Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury(2013)85 cited
- → Small molecules that target group II introns are potent antifungal agents(2018)81 cited
- → Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors(2018)54 cited
- → Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications(2004)48 cited
- → Chemoenzymic Synthesis of 4-Substituted Riboses. S-(4'-Methyladenosyl)-L-homocysteine(1994)29 cited
- → Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications(2009)26 cited
- → Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis(2014)20 cited
- → ChemInform Abstract: Chemoenzymatic Synthesis of 4‐Substituted Riboses. S‐(4′‐ Methyladenosyl)‐L‐homocysteine.(1995)3 cited
- → Applications of enzymes in the synthesis of bioactive polyols(1992)1 cited