David R. Tortolani
Bristol-Myers Squibb (United States)(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Retinoids in leukemia and cellular processes, Estrogen and related hormone effects, HIV Research and Treatment, Click Chemistry and Applications
Most-Cited Works
- → Two distinct actions of retinoid-receptor ligands(1996)196 cited
- → Synthesis, Oral Bioavailability Determination, and in vitro Evaluation of Prodrugs of the Antiviral Agent 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA)(1994)141 cited
- → Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine(1992)120 cited
- → Preparation of 1-(2,3-dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine (d4T) and 2',3'-dideoxyadenosine (ddA): general methods for the synthesis of 2',3'-olefinic and 2',3'-dideoxy nucleoside analogs active against HIV(1989)92 cited
- → Rational design of RAR‐selective ligands revealed by RARβ crystal stucture(2004)86 cited
- → Retinoic Acid Receptor β,γ-Selective Ligands: Synthesis and Biological Activity of 6-Substituted 2-Naphthoic Acid Retinoids(1996)56 cited
- → Small Molecule Antagonist of Leukocyte Function Associated Antigen-1 (LFA-1): Structure−Activity Relationships Leading to the Identification of 6-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic Acid (BMS-688521)(2010)43 cited
- → Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design(2021)42 cited
- → Aminotriazine 5-HT7 antagonists(2004)36 cited
- → A solid phase synthesis of miconazole analogs via an iodoetherification reaction(1996)32 cited