James H. Nettles
Emory University(US)
Publications by Year
Research Areas
Microtubule and mitosis dynamics, HIV/AIDS drug development and treatment, Cancer Treatment and Pharmacology, Computational Drug Discovery Methods, HIV Research and Treatment
Most-Cited Works
- → Drugs that target dynamic microtubules: A new molecular perspective(2011)523 cited
- → The Binding Mode of Epothilone A on α,ß-Tubulin by Electron Crystallography(2004)419 cited
- → Polyoxometalate HIV-1 Protease Inhibitors. A New Mode of Protease Inhibition(2001)366 cited
- → The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density(2001)363 cited
- → Bridging Chemical and Biological Space: “Target Fishing” Using 2D and 3D Molecular Descriptors(2006)208 cited
- → Microtubule-interacting drugs for cancer treatment(2003)178 cited
- → Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of β-tubulin (Asp26Glu) and less stable microtubules(2006)146 cited
- → “Bayes Affinity Fingerprints” Improve Retrieval Rates in Virtual Screening and Define Orthogonal Bioactivity Space: When Are Multitarget Drugs a Feasible Concept?(2006)112 cited
- → Enrichment of High-Throughput Screening Data with Increasing Levels of Noise Using Support Vector Machines, Recursive Partitioning, and Laplacian-Modified Naive Bayesian Classifiers(2005)104 cited
- → Massage therapy decreases cancer‐related fatigue: Results from a randomized early phase trial(2017)79 cited