Akihiro Ohashi
National Cancer Centre Japan(JP)
Publications by Year
Research Areas
Lung Cancer Treatments and Mutations, Cancer Genomics and Diagnostics, DNA Repair Mechanisms, Microtubule and mitosis dynamics, Cancer-related Molecular Pathways
Most-Cited Works
- → Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2(2006)855 cited
- → Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells(2015)198 cited
- → TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma(2018)138 cited
- → Functional Evaluation and Cancer Risk Assessment of BRCA2 Unclassified Variants(2005)114 cited
- → Single-Cell Analyses Reveal Diverse Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer(2021)102 cited
- → Combination treatment with a PI3K/Akt/mTOR pathway inhibitor overcomes resistance to anti-HER2 therapy in PIK3CA-mutant HER2-positive breast cancer cells(2020)85 cited
- → Fanconi Anemia Complementation Group D2 (FANCD2) Functions Independently of BRCA2- and RAD51-associated Homologous Recombination in Response to DNA Damage(2005)79 cited
- → Inactivation of Brca2 Promotes Trp53-Associated but Inhibits KrasG12D-Dependent Pancreatic Cancer Development in Mice(2011)74 cited
- → TAS6417/CLN-081 Is a Pan-Mutation–Selective EGFR Tyrosine Kinase Inhibitor with a Broad Spectrum of Preclinical Activity against Clinically Relevant EGFR Mutations(2019)71 cited
- → Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor(2019)67 cited