Michael S. Wolfe
University of Wisconsin–Madison(US)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Cholinesterase and Neurodegenerative Diseases, Computational Drug Discovery Methods, Cellular transport and secretion, Supramolecular Self-Assembly in Materials
Most-Cited Works
- → A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain(1999)2,092 cited
- → Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity(1999)1,916 cited
- → c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma(2006)884 cited
- → γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2(2003)751 cited
- → Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1(2000)518 cited
- → A Portrait of Alzheimer Secretases--New Features and Familiar Faces(2001)492 cited