Charles M. Blazey
Exelixis (United States)(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Analytical Chemistry and Chromatography, Heat shock proteins research, Melanoma and MAPK Pathways, Synthetic Organic Chemistry Methods
Most-Cited Works
- → Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973)(2012)162 cited
- → Discovery of XL888: A novel tropane-derived small molecule inhibitor of HSP90(2012)77 cited
- → Discovery of a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR)(2013)65 cited
- → Alkyl side-chain derivatives of sordaricin as potent antifungal agents against yeast(1998)29 cited
- → Pyrazolopyrimidines as dual Akt/p70S6K inhibitors(2012)28 cited
- → Design and evaluation of a series of pyrazolopyrimidines as p70S6K inhibitors(2012)24 cited
- → Regiochemistry in 1,3-Dipolar Cycloadditions of the Azomethine Ylide Formed from Diethyl Aminomalonate and Paraformaldehyde(2001)14 cited
- → Determination of the Absolute Stereochemistry of (−)-Galbonolide A(1997)13 cited
- → Application of a novel directing effect in an organocopper/orthoester reaction to the synthesis of deuterium labeled unsaturated esters(1997)5 cited
- → ChemInform Abstract: Determination of the Absolute Stereochemistry of (‐)‐Galbonolide A.(1997)1 cited