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Brian M. McKeever | doi.page

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Brian M. McKeever

The University of Sydney(AU)Sydney Hospital(AU)

Publications by Year

Research Areas

Enzyme Structure and Function, Hormonal Regulation and Hypertension, Receptor Mechanisms and Signaling, HIV/AIDS drug development and treatment, Peroxisome Proliferator-Activated Receptors

Most-Cited Works

→ Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1(1989)888 cited
→ A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia(2019)438 cited
→ Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution.(1990)246 cited
→ Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution.(1989)232 cited
→ Crystal Structure of Inhibitor-Bound Human 5-Lipoxygenase-Activating Protein(2007)224 cited
→ Protein Crystal Growth in Microgravity(1989)191 cited
→

Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl design

(1992)

167 cited

→ Structure-Based Design of β-Site APP Cleaving Enzyme 1 (BACE1) Inhibitors for the Treatment of Alzheimer’s Disease(2013)132 cited

→ New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thiophene-2-sulfonamides(1991)116 cited

→ The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1(2001)84 cited