M. Luisa Rosado
Central University of the Caribbean(PR)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Receptor Mechanisms and Signaling, Synthesis and Biological Evaluation, Synthesis of heterocyclic compounds, Phenothiazines and Benzothiazines Synthesis and Activities
Most-Cited Works
- → Synthesis and Structure−Activity Relationships of a New Model of Arylpiperazines. 2. Three-Dimensional Quantitative Structure−Activity Relationships of Hydantoin−Phenylpiperazine Derivatives with Affinity for 5-HT1A and α1 Receptors. A Comparison of CoMFA Models(1997)64 cited
- → Synthesis and Structure−Activity Relationships of a New Model of Arylpiperazines. 1. 2-[[4-(o-Methoxyphenyl)piperazin-1-yl]methyl]-1,3- dioxoperhydroimidazo[1,5-a]pyridine: A Selective 5-HT1A Receptor Agonist(1996)63 cited
- → Synthesis and Structure−Activity Relationships of a New Model of Arylpiperazines. 6. Study of the 5-HT1A/α1-Adrenergic Receptor Affinity by Classical Hansch Analysis, Artificial Neural Networks, and Computational Simulation of Ligand Recognition(2000)56 cited
- → Tobacco cembranoids block behavioral sensitization to nicotine and inhibit neuronal acetylcholine receptor function(2001)40 cited
- → Comparative receptor mapping of serotoninergic 5-HT3 and 5-HT4 binding sites*(1997)34 cited
- → Preclinical pharmacology of B-20991, a 5-HT1A receptor agonist with anxiolytic activity(1998)15 cited
- → Design and synthesis of 2-[4-[4-(m-(ethylsulfonamido)-phenyl)piperazin-1-yl]butyl]-1,3-dioxoperhydropyrrolo[1,2-c]imidazole (EF-7412) using neural networks. A selective derivative with mixed antagonist properties(1999)12 cited
- → ChemInform Abstract: Design and Synthesis of 2‐[4‐[4‐(m‐(Ethylsulfonamido)‐phenyl)piperazin‐1‐yl]butyl] ‐1,3‐dioxoperhydropyrrolo[1,2‐c]imidazole (EF‐7412) Using Neural Networks. A Selective Derivative with Mixed 5‐HT1A/D2 Antagonist Properties.(1999)
- → ChemInform Abstract: Synthesis and Structure‐Activity Relationships of a New Model of Arylpiperazines. Part 1. 2‐((4‐(o‐Methoxyphenyl)piperazin‐1‐yl)methyl)‐ 1,3‐dioxoperhydroimidazo(1,5‐a)pyridine: A Selective 5‐HT1A Receptor Agonist.(1997)
- → Application of Artificial Neural Networks in QSAR of a New Model of Phenylpiperazine Derivatives1 with Affinity for 5-HT1A and αl Receptors: A Comparision of ANN Models(2000)