Pearl S. Huang
Io Therapeutics (United States)(US)
Publications by Year
Research Areas
Melanoma and MAPK Pathways, PI3K/AKT/mTOR signaling in cancer, Synthesis and biological activity, Cancer-related Molecular Pathways, Cancer Mechanisms and Therapy
Most-Cited Works
- → Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer(2009)3,105 cited
- → Targeted anti-mitotic therapies: can we improve on tubulin agents?(2007)470 cited
- → Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product(1991)332 cited
- → Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity(2008)296 cited
- → EMT is the dominant program in human colon cancer(2011)278 cited
- → Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic BRAF by the Kinase Inhibitor SB-590885(2006)262 cited
- → Antitumor activity of an allosteric inhibitor of centromere-associated protein-E(2010)254 cited
- → A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors(2010)152 cited
- → Antitumor Activity in RAS -Driven Tumors by Blocking AKT and MEK(2014)135 cited
- → Protein domains governing interactions between E2F, the retinoblastoma gene product, and human papillomavirus type 16 E7 protein.(1993)125 cited