A. Sieghart
Genomics England(GB)
Publications by Year
Research Areas
Cancer Genomics and Diagnostics, Genomics and Rare Diseases, Epigenetics and DNA Methylation, Mitochondrial Function and Pathology, RNA and protein synthesis mechanisms
Most-Cited Works
- → Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli(2020)1,086 cited
- → Substitution mutational signatures in whole-genome–sequenced cancers in the UK population(2022)273 cited
- → A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage(2021)165 cited
- → Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans(2020)126 cited
- → Origins and impact of extrachromosomal DNA(2024)122 cited
- → Signatures of TOP1 transcription-associated mutagenesis in cancer and germline(2022)81 cited
- → Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features(2022)73 cited
- → Normal and pathogenic variation of RFC1 repeat expansions: implications for clinical diagnosis(2023)67 cited
- → Comparison of in silico strategies to prioritize rare genomic variants impacting RNA splicing for the diagnosis of genomic disorders(2021)64 cited
- → Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma(2021)60 cited