Pengda Liu
University of North Carolina at Chapel Hill(US)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, interferon and immune responses, PI3K/AKT/mTOR signaling in cancer, Cancer-related Molecular Pathways, Protein Degradation and Inhibitors
Most-Cited Works
- → Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer(2021)685 cited
- → Roles of F-box proteins in cancer(2014)534 cited
- → CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1(2010)397 cited
- → PtdIns(3,4,5) P 3-Dependent Activation of the mTORC2 Kinase Complex(2015)375 cited
- → Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus(2014)365 cited
- → Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4(2017)333 cited
- → Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis(2013)254 cited
- → mTOR Drives Its Own Activation via SCFβTrCP-Dependent Degradation of the mTOR Inhibitor DEPTOR(2011)247 cited
- → Cytosolic DNA sensing by cGAS: regulation, function, and human diseases(2021)230 cited
- → Therapeutic Implications for Overcoming Radiation Resistance in Cancer Therapy(2015)227 cited