Alun Bermingham
Revolution Medicines (United States)(US)
Publications by Year
Research Areas
Signaling Pathways in Disease, Antibiotic Resistance in Bacteria, Biochemical and Molecular Research, Cancer therapeutics and mechanisms, Peptidase Inhibition and Analysis
Most-Cited Works
- → The folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery(2002)285 cited
- → Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530(2009)254 cited
- → Prevention of MKK6-Dependent Activation by Binding to p38α MAP Kinase(2005)89 cited
- → Vinylogous Ureas as a Novel Class of Inhibitors of Reverse Transcriptase-Associated Ribonuclease H Activity(2008)61 cited
- → Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae – Identification of LYS228(2018)58 cited
- → Structure-Activity Analysis of Vinylogous Urea Inhibitors of Human Immunodeficiency Virus-Encoded Ribonuclease H(2010)47 cited
- → Equilibrium and Kinetic Studies of Substrate Binding to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase fromEscherichia coli(2000)40 cited
- → Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis(2020)39 cited
- → Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae(2018)39 cited
- → Abstract 1260: First-in-class, orally bioavailable KRASG12V(ON) tri-complex inhibitors, as single agents and in combinations, drive profound anti-tumor activity in preclinical models of KRASG12V mutant cancers(2021)33 cited