Timothy D. Owens
Brown University(US)
Publications by Year
Research Areas
Chronic Lymphocytic Leukemia Research, Chemical Synthesis and Analysis, Synthesis and Catalytic Reactions, Fibroblast Growth Factor Research, Peptidase Inhibition and Analysis
Most-Cited Works
- → N-tert-Butanesulfinyl Imines: Versatile Intermediates for the Asymmetric Synthesis of Amines(2002)821 cited
- → Prolonged and tunable residence time using reversible covalent kinase inhibitors(2015)426 cited
- → RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents(2012)140 cited
- → Synthesis, Utility, and Structure of Novel Bis(sulfinyl)imidoamidine Ligands for Asymmetric Lewis Acid Catalysis(2001)119 cited
- → New Synthetic Technology for Efficient Construction of α-Hydroxy-β-amino Amides via the Passerini Reaction1(2000)116 cited
- → Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease(2021)113 cited
- → Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis(2014)107 cited
- → Discovery of the Irreversible Covalent FGFR Inhibitor 8-(3-(4-Acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (PRN1371) for the Treatment of Solid Tumors(2017)95 cited
- → Bruton’s Tyrosine Kinase Inhibitors: Approaches to Potent and Selective Inhibition, Preclinical and Clinical Evaluation for Inflammatory Diseases and B Cell Malignancies(2012)87 cited
- → The Preparation and Utility of Bis(sulfinyl)imidoamidine Ligands for the Copper-Catalyzed Diels−Alder Reaction(2002)86 cited