Matthew J. Kostura
Durham VA Medical Center(US)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Cancer, Hypoxia, and Metabolism, Click Chemistry and Applications, Computational Drug Discovery Methods, Protein Degradation and Inhibitors
Most-Cited Works
- → A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes(1992)2,559 cited
- → Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein(1987)1,074 cited
- → Identification of a monocyte specific pre-interleukin 1 beta convertase activity.(1989)510 cited
- → The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro(1987)489 cited
- → Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice(1995)367 cited
- → IL-1-converting enzyme requires aspartic acid residues for processing of the IL-1 beta precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha(1991)322 cited
- → Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase(1999)196 cited
- → Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI.(1989)194 cited
- → The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy.(1995)154 cited
- → Pyrroles and other heterocycles as inhibitors of P38 kinase(1998)117 cited