Peter K. S. Siegl
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Renin-Angiotensin System Studies, Cardiac electrophysiology and arrhythmias, Ion channel regulation and function, Synthesis and Biological Evaluation
Most-Cited Works
- → Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development(2003)1,520 cited
- → A novel multiple-stage antimalarial agent that inhibits protein synthesis(2015)454 cited
- → Quinolone-3-Diarylethers: A New Class of Antimalarial Drug(2013)298 cited
- → Torcetrapib‐induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone(2008)285 cited
- → Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action.(1991)284 cited
- → Drug attrition during pre-clinical and clinical development: Understanding and managing drug-induced cardiotoxicity(2013)204 cited
- → BRL 34915 (cromakalim) activates ATP-sensitive K+ current in cardiac muscle.(1988)191 cited
- → Inhibition of Na+/Ca2+ exchange in membrane vesicle and papillary muscle preparations from guinea pig heart by analogs of amiloride.(1984)188 cited
- → Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists(1991)161 cited
- → UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria(2018)136 cited