Céline Bonnefous
Araim Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Estrogen and related hormone effects, Prostate Cancer Treatment and Research, Histone Deacetylase Inhibitors Research, Computational Drug Discovery Methods, Protein Degradation and Inhibitors
Most-Cited Works
- → ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment(2012)654 cited
- → Identification of GDC-0810 (ARN-810), an Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) that Demonstrates Robust Activity in Tamoxifen-Resistant Breast Cancer Xenografts(2015)245 cited
- → Synthesis, characterization, and first successful monkey imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) PET radiotracers(2005)152 cited
- → The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer(2016)117 cited
- → Maximizing ER-α Degradation Maximizes Activity in a Tamoxifen-Resistant Breast Cancer Model: Identification of GDC-0927(2018)74 cited
- → Discovery of Inducible Nitric Oxide Synthase (iNOS) Inhibitor Development Candidate KD7332, Part 1: Identification of a Novel, Potent, and Selective Series of Quinolinone iNOS Dimerization Inhibitors that are Orally Active in Rodent Pain Models(2009)69 cited
- → Six-Membered Ring Chelate Complexes of Ru(II): Structural and Photophysical Effects(2007)59 cited
- → Discovery of Dual Inducible/Neuronal Nitric Oxide Synthase (iNOS/nNOS) Inhibitor Development Candidate 4-((2-Cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) Part 2: Identification of a Novel, Potent, and Selective Series of Benzimidazole-Quinolinone iNOS/nNOS Dimerization Inhibitors That Are Orally Active in Pain Models(2010)58 cited
- → Cyclometalated Complexes of Ru(II) with 2-Aryl Derivatives of Quinoline and 1,10-Phenanthroline(2001)50 cited
- → Biphenyl-indanones: Allosteric potentiators of the metabotropic glutamate subtype 2 receptor(2005)50 cited