LeeAnn Machiesky
AstraZeneca (United States)(US)
Publications by Year
Research Areas
Monoclonal and Polyclonal Antibodies Research, Protein purification and stability, Glycosylation and Glycoproteins Research, CAR-T cell therapy research, T-cell and B-cell Immunology
Most-Cited Works
- → ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome(2021)169 cited
- → Characterization of IgG1 Fc Deamidation at Asparagine 325 and Its Impact on Antibody-dependent Cell-mediated Cytotoxicity and FcγRIIIa Binding(2020)46 cited
- → Fc-mediated functions of nirsevimab complement direct respiratory syncytial virus neutralization but are not required for optimal prophylactic protection(2023)28 cited
- → Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancer(2021)28 cited
- → Monovalent IgG4 molecules(2013)19 cited
- → Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies(2022)17 cited
- → A rapid lateral flow immunoassay for identity testing of biotherapeutics(2019)10 cited
- → A high yielding IFNAR1 ECD mammalian expression process for use in autoimmune disease drug development(2019)3 cited
- → Development of a mechanism of action reflective and robust potency assay for a therapeutic antibody against alpha toxin using rabbit erythrocytes(2020)2 cited