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André B. P. Kuilenburg | doi.page

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André B. P. Kuilenburg

Dutch Cancer Society(NL)Amsterdam Neuroscience(NL)Isala(NL)Amsterdam University Medical Centers(NL)Cancer Center Amsterdam(NL)Vrije Universiteit Amsterdam(NL)University of Amsterdam(NL)Amsterdam UMC Location Vrije Universiteit Amsterdam(NL)

Publications by Year

Research Areas

Biochemical and Molecular Research, Metabolism and Genetic Disorders, Colorectal Cancer Treatments and Studies, Neonatal Health and Biochemistry, Cancer therapeutics and mechanisms

Most-Cited Works

→ Histone deacetylases (HDACs): characterization of the classical HDAC family(2003)3,077 cited
→ Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil(2004)483 cited
→ Thalassemia Syndromes(2009)475 cited
→ Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.(1996)410 cited
→ DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis(2018)408 cited
→ Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data(2015)368 cited

Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene.(2000)

→ Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency(1999)282 cited

Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency.(2001)

Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls.(2001)