Robert E. Babine
Orphagen Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Coagulation, Bradykinin, Polyphosphates, and Angioedema, Mast cells and histamine, Computational Drug Discovery Methods, Carbohydrate Chemistry and Synthesis, Click Chemistry and Applications
Most-Cited Works
- → Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design(1997)893 cited
- → Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies(1998)111 cited
- → Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies(1998)92 cited
- → Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2(2005)72 cited
- → Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants(2006)70 cited
- → Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine(2006)63 cited
- → The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine(2004)63 cited
- → SAR Exploration Guided by LE and Fsp 3 : Discovery of a Selective and Orally Efficacious RORγ Inhibitor(2015)58 cited
- → Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa(2006)58 cited
- → Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions(2004)56 cited