Kara M. Hoar
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Ubiquitin and proteasome pathways, Cancer-related Molecular Pathways, Photosynthetic Processes and Mechanisms, Immunotherapy and Immune Responses
Most-Cited Works
- → A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment(2018)441 cited
- → Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase(2007)413 cited
- → Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays(2011)300 cited
- → Vaccination of Cancer Patients Against Telomerase Induces Functional Antitumor CD8+ T Lymphocytes(2004)253 cited
- → MLN8054, a Small-Molecule Inhibitor of Aurora A, Causes Spindle Pole and Chromosome Congression Defects Leading to Aneuploidy(2007)202 cited
- → Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer(2021)197 cited
- → Localization of Human TACC3 to Mitotic Spindles Is Mediated by Phosphorylation on Ser558 by Aurora A: A Novel Pharmacodynamic Method for Measuring Aurora A Activity(2007)128 cited
- → Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia(2020)121 cited
- → MLN8054, an Inhibitor of Aurora A Kinase, Induces Senescence in Human Tumor Cells Both In vitro and In vivo(2010)117 cited
- → MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors(2015)108 cited