Alison E. Shone
Publications by Year
Research Areas
Malaria Research and Control, Computational Drug Discovery Methods, Synthesis and biological activity, HIV/AIDS drug development and treatment, Cancer therapeutics and mechanisms
Most-Cited Works
- → Antimalarial pharmacology and therapeutics of atovaquone(2013)198 cited
- → Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria(2012)156 cited
- → Probing the Validity of the Probe-to-Bone Test in the Diagnosis of Osteomyelitis of the Foot in Diabetes(2006)135 cited
- → Identification of a 1,2,4,5‐Tetraoxane Antimalarial Drug‐Development Candidate (RKA 182) with Superior Properties to the Semisynthetic Artemisinins(2010)123 cited
- → Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)(2012)109 cited
- → Candidate Selection and Preclinical Evaluation of N - tert -Butyl Isoquine (GSK369796), An Affordable and Effective 4-Aminoquinoline Antimalarial for the 21st Century(2009)84 cited
- → Two-Step Synthesis of Achiral Dispiro-1,2,4,5-tetraoxanes with Outstanding Antimalarial Activity, Low Toxicity, and High-Stability Profiles(2008)82 cited
- → Targeting the Mitochondrial Electron Transport Chain ofPlasmodium Falciparum:New Strategies Towards the Development of Improved Antimalarials for the Elimination Era(2013)66 cited
- → Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates(2009)65 cited
- → Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable “Back-Up” Compound for N-tert-Butyl Isoquine(2009)61 cited