John Xi Chen
Memorial Sloan Kettering Cancer Center(US)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Mitochondrial Function and Pathology, Metabolism and Genetic Disorders, Neuroscience and Neuropharmacology Research, Neuroinflammation and Neurodegeneration Mechanisms
Most-Cited Works
- → Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease(2008)925 cited
- → Receptor for Advanced Glycation End Product-Dependent Activation of p38 Mitogen-Activated Protein Kinase Contributes to Amyloid-β-Mediated Cortical Synaptic Dysfunction(2008)198 cited
- → Inhibition of Amyloid-β (Aβ) Peptide-Binding Alcohol Dehydrogenase-Aβ Interaction Reduces Aβ Accumulation and Improves Mitochondrial Function in a Mouse Model of Alzheimer's Disease(2011)181 cited
- → Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell(2013)179 cited
- → Role of Mitochondrial Amyloid-β in Alzheimer's Disease(2010)177 cited
- → Amyloid-β-Induced Mitochondrial Dysfunction(2007)164 cited
- → Cyclophilin D Deficiency Rescues Axonal Mitochondrial Transport in Alzheimer’s Neurons(2013)118 cited
- → Decreased Proteolytic Activity of the Mitochondrial Amyloid-β Degrading Enzyme, PreP Peptidasome, in Alzheimer's Disease Brain Mitochondria(2011)116 cited
- → Cyclophilin D deficiency rescues Aβ-impaired PKA/CREB signaling and alleviates synaptic degeneration(2013)85 cited
- → Increased neuronal PreP activity reduces Aβ accumulation, attenuates neuroinflammation and improves mitochondrial and synaptic function in Alzheimer disease's mouse model(2015)82 cited